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Tag: narrow therapeutic index

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Prescriber Attitudes Toward NTI Drugs and Substitution: What Doctors Really Think

Prescriber Attitudes Toward NTI Drugs and Substitution: What Doctors Really Think

by Lila Thorne

Prescribers remain divided on generic substitution for narrow therapeutic index (NTI) drugs like warfarin, lithium, and tacrolimus. Despite FDA assurances, many doctors prefer brand-name versions due to stability concerns, inconsistent communication, and state-level restrictions.

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